Equine Science by Zoe Davies

Author:Zoe Davies [Davies, Zoe]
Language: eng
Format: epub
ISBN: 9781118741160
Publisher: John Wiley & Sons, Inc.
Published: 2017-08-17T00:00:00+00:00

Glucocorticoids

Zona fasciculata cells secrete glucocorticoids, including cortisol, cortisone and corticosterone which control glucose metabolism. Glucocorticoids also have anti-inflammatory effects by inhibiting basophils, the white blood cells that are part of the inflammatory response. Glucocorticoids increase gluconeogenesis in the liver by:

• Glucose synthesis – converting some amino acids or lactic acid to glucose

• Protein breakdown – increasing the rate of protein breakdown mostly in muscle to increase amino acids in the blood for gluconeogenesis

• Triglycerides breakdown – by increasing the rate of triglyceride breakdown in adipose (fat) tissue, fatty acids are used for gluconeogenesis

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